Zerit (Stavudine)
Drug Uses

This medicine is a nucleoside analogue antiviral used in combination with other medicines to manage human immunodeficiency virus (HIV) infection.
How to use

The recommended dose for adults is 40 mg twice daily for those weighing 60 kg or more and 30 mg twice daily if less than 60 kg. Children weighing less than 30 kg should receive 1 mg/kg. Children weighing 30 kg or more should be treated like adults. Zerit may be administered without regard to meals.
Drug Class and Mechanism

Zerit is an oral medication that is used for the treatment of infections with the human immunodeficiency virus (HIV). It is in a class of drugs called reverse transcriptase inhibitors which also includes zalcitabine (Hivid), zidovudine (Retrovir), didanosine (Videx), and lamivudine (Epivir). During infection with HIV, the HIV virus multiplies within the body's cells. The newly-formed viruses then are released from the cells and spread throughout the body where they infect other cells. In this manner, the infection continually spreads to new, uninfected cells that the body is continually producing, and HIV infection is perpetuated. When producing new viruses, the HIV virus must manufacture new DNA for each virus. Reverse transcriptase is the enzyme that the virus uses to form this new DNA. Specifically, zerit is converted within the body to its active form (stavudine triphosphate). This active form is similar to thymidine triphosphate, a chemical that is required by the HIV virus to make new DNA. The reverse transcriptase uses stavudine triphosphate instead of thymidine triphosphate for making DNA, and it is the stavudine triphosphate that interferes with the reverse transcriptase. Zerit does not kill existing HIV virus and it is not a cure for HIV.
Missed Dose

If you miss a dose of this medicine, take it as soon as you remember. If it is within 2 hours of your next dose, skip the missed dose and go back to your regular dosing schedule.
Storage

Store capsules at room temperature, 15-30 degrees C (59-86 degrees F). The dry powder for oral solution should be kept at room temperature and away form moisture. Solutions should be refrigerated.

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Zerit (Stavudine)
Drug Uses

This medicine is a nucleoside analogue antiviral used in combination with other medicines to manage human immunodeficiency virus (HIV) infection.
How to use

The recommended dose for adults is 40 mg twice daily for those weighing 60 kg or more and 30 mg twice daily if less than 60 kg. Children weighing less than 30 kg should receive 1 mg/kg. Children weighing 30 kg or more should be treated like adults. Zerit may be administered without regard to meals.
Drug Class and Mechanism

Zerit is an oral medication that is used for the treatment of infections with the human immunodeficiency virus (HIV). It is in a class of drugs called reverse transcriptase inhibitors which also includes zalcitabine (Hivid), zidovudine (Retrovir), didanosine (Videx), and lamivudine (Epivir). During infection with HIV, the HIV virus multiplies within the body's cells. The newly-formed viruses then are released from the cells and spread throughout the body where they infect other cells. In this manner, the infection continually spreads to new, uninfected cells that the body is continually producing, and HIV infection is perpetuated. When producing new viruses, the HIV virus must manufacture new DNA for each virus. Reverse transcriptase is the enzyme that the virus uses to form this new DNA. Specifically, zerit is converted within the body to its active form (stavudine triphosphate). This active form is similar to thymidine triphosphate, a chemical that is required by the HIV virus to make new DNA. The reverse transcriptase uses stavudine triphosphate instead of thymidine triphosphate for making DNA, and it is the stavudine triphosphate that interferes with the reverse transcriptase. Zerit does not kill existing HIV virus and it is not a cure for HIV.
Missed Dose

If you miss a dose of this medicine, take it as soon as you remember. If it is within 2 hours of your next dose, skip the missed dose and go back to your regular dosing schedule.
Storage

Store capsules at room temperature, 15-30 degrees C (59-86 degrees F). The dry powder for oral solution should be kept at room temperature and away form moisture. Solutions should be refrigerated.

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Zerit (Stavudine)
Drug Uses

This medicine is a nucleoside analogue antiviral used in combination with other medicines to manage human immunodeficiency virus (HIV) infection.
How to use

The recommended dose for adults is 40 mg twice daily for those weighing 60 kg or more and 30 mg twice daily if less than 60 kg. Children weighing less than 30 kg should receive 1 mg/kg. Children weighing 30 kg or more should be treated like adults. Zerit may be administered without regard to meals.
Drug Class and Mechanism

Zerit is an oral medication that is used for the treatment of infections with the human immunodeficiency virus (HIV). It is in a class of drugs called reverse transcriptase inhibitors which also includes zalcitabine (Hivid), zidovudine (Retrovir), didanosine (Videx), and lamivudine (Epivir). During infection with HIV, the HIV virus multiplies within the body's cells. The newly-formed viruses then are released from the cells and spread throughout the body where they infect other cells. In this manner, the infection continually spreads to new, uninfected cells that the body is continually producing, and HIV infection is perpetuated. When producing new viruses, the HIV virus must manufacture new DNA for each virus. Reverse transcriptase is the enzyme that the virus uses to form this new DNA. Specifically, zerit is converted within the body to its active form (stavudine triphosphate). This active form is similar to thymidine triphosphate, a chemical that is required by the HIV virus to make new DNA. The reverse transcriptase uses stavudine triphosphate instead of thymidine triphosphate for making DNA, and it is the stavudine triphosphate that interferes with the reverse transcriptase. Zerit does not kill existing HIV virus and it is not a cure for HIV.
Missed Dose

If you miss a dose of this medicine, take it as soon as you remember. If it is within 2 hours of your next dose, skip the missed dose and go back to your regular dosing schedule.
Storage

Store capsules at room temperature, 15-30 degrees C (59-86 degrees F). The dry powder for oral solution should be kept at room temperature and away form moisture. Solutions should be refrigerated.

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Drug Uses

Zelnorm is used for the short-term treatment of women with IBS whose primary bowel symptom is constipation. It also is approved for the treatment of chronic, idiopathic constipation in men and women less than 65 years of age.
How to use

The usual dose of zelnorm is 6 mg twice daily, most frequently for 4 to 12 weeks. Zelnorm can be taken with or without food. Older persons do not require lower doses than younger persons.
Drug Class and Mechanism

Zelnorm is an oral medication for the treatment of constipation and constipation-predominant irritable bowel syndrome (IBS) in women. IBS is a chronic gastrointestinal disorder characterized by recurrent abdominal pain or discomfort and altered bowel function which may be either constipation or diarrhea. As many as 20% of American adults may suffer from IBS. Contractions of the intestinal muscles, primarily those of the colon, control the movement of food through the intestine. In constipated patients, there are fewer contractions than in persons without constipation. An important factor that controls the contractions is serotonin. Serotonin is a chemical manufactured by nerves in the intestine. It is released by the nerves and then travels and binds to receptors on the surface of nearby nerves. It is a "neurotransmitter," a chemical messenger, that is, a chemical that nerves use to communicate with each other. When it binds to receptors on the nerves that control contractions of the intestinal muscles, serotonin can either promote or prevent contractions depending on the type of receptor it binds to. Binding to some types of receptors causes contractions, and binding to other types of receptors blocks contractions. The serotonin 5-HT4 receptor is a receptor that prevents contractions when serotonin binds to it. Zelnorm blocks the 5-HT4 receptor and prevents serotonin from binding to it. As a result, contractions increase. The increased contractions speed the transit of digesting food and reverse the constipation. In addition, zelnorm reduces the sensitivity of the intestinal pain-sensing nerves and can thereby reduce the perception of pain.
Missed Dose

If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Storage

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Zelnorm (Tegaserod)
Drug Uses

Zelnorm is used for the short-term treatment of women with IBS whose primary bowel symptom is constipation. It also is approved for the treatment of chronic, idiopathic constipation in men and women less than 65 years of age.
How to use

The usual dose of zelnorm is 6 mg twice daily, most frequently for 4 to 12 weeks. Zelnorm can be taken with or without food. Older persons do not require lower doses than younger persons.
Drug Class and Mechanism

Zelnorm is an oral medication for the treatment of constipation and constipation-predominant irritable bowel syndrome (IBS) in women. IBS is a chronic gastrointestinal disorder characterized by recurrent abdominal pain or discomfort and altered bowel function which may be either constipation or diarrhea. As many as 20% of American adults may suffer from IBS. Contractions of the intestinal muscles, primarily those of the colon, control the movement of food through the intestine. In constipated patients, there are fewer contractions than in persons without constipation. An important factor that controls the contractions is serotonin. Serotonin is a chemical manufactured by nerves in the intestine. It is released by the nerves and then travels and binds to receptors on the surface of nearby nerves. It is a "neurotransmitter," a chemical messenger, that is, a chemical that nerves use to communicate with each other. When it binds to receptors on the nerves that control contractions of the intestinal muscles, serotonin can either promote or prevent contractions depending on the type of receptor it binds to. Binding to some types of receptors causes contractions, and binding to other types of receptors blocks contractions. The serotonin 5-HT4 receptor is a receptor that prevents contractions when serotonin binds to it. Zelnorm blocks the 5-HT4 receptor and prevents serotonin from binding to it. As a result, contractions increase. The increased contractions speed the transit of digesting food and reverse the constipation. In addition, zelnorm reduces the sensitivity of the intestinal pain-sensing nerves and can thereby reduce the perception of pain.
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Zanaflex is a muscle relaxant is used to help relax certain muscles in your body. It relieves the spasms and increased muscle tone caused by medical problems such as multiple sclerosis or spinal injury. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
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Tizanidine is an agonist at (alpha) 2 -adrenergic receptor sites and presumably reduces spasticity by increasing presynaptic inhibition of motor neurons. In animal models, tizanidine has no direct effect on skeletal muscle fibers or the neuromuscular junction, and no major effect on monosynaptic spinal reflexes. The effects of tizanidine are greatest on polysynaptic pathways. The overall effect of these actions is thought to reduce facilitation of spinal motor neurons.

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Take sparfloxacin tablets by mouth. Swallow tablets whole with a full glass of water. Sparfloxacin may be taken with or without food. Do not take with magnesium/aluminum antacids, sucralfate, Videx® (didanosine) chewable/buffered tablets or pediatric powder, or with other products containing iron or zinc. These products may be taken 4 hours after taking sparfloxacin. Take your doses at regular intervals; preferably at the same time each day. Do not take your medicine more often than directed. Finish the full course prescribed by your prescriber or health care professional even if you think your condition is better. Do not stop taking except on your prescriber's advice.

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